THE BENEFITS OF WHOLE-GENOME SEQUENCING NOW AND IN THE FUTURE
1️⃣ Our knowledge of all the strong signals in the human genome is in fact increasing steadily. As a consequence of the continuing new discoveries, although a person’s genome may not reveal obvious strong signals on first analysis, part of the value of genomics is that data can be stored and analyzed as knowledge accrues, […]
WHOLE GENOME SEQUENCING IN THE CLINIC: EMPOWERMENT OR TOO MUCH INFORMATION?
1️⃣ Next-generation sequencing encompasses several approaches: whole genome sequencing, whole exome sequencing and targeted sequencing.3–5 Whole genome sequencing reports all nucleotidebases in the entire genome, whole exome sequencing reports only the protein-coding regions (exons), and simpler targeted panels use next-generation sequencing chemistry to slice out information on predetermined disease-associated genes. 2️⃣ The hundreds of thousands […]