1️⃣ UC-MSC can be obtained free and amplify to a large number. It has been reported that UC-MSC transplantation alleviate symptoms of various autoimmune diseases.
2️⃣ UC-MSCs show a more beneficial immunogenic profile and stronger overall immunosuppressive potential than BM-MSCs.
3️⃣ After UC-MSC therapy, liver function was improved, that serum albumin levels increased and bilirubin levels decreased. UC-MSC treatment also improved liver function and patient’s quality of life in primary biliary cirrhosis (PBC). UC-MSC therapy lowered serum alkaline phosphatase and γ-glutamyltransferase levels and alleviate fatigue and pruritus symptom in PBC patients. Comparing to BM-MSC, adipose-derived stromal cells (ADSCs) can be obtained from healthy donors freely and cultured to expand sufficient numbers.
[By Celebre Pro Medic Sdn Bhd 20220114]